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Inadequate details exists for making correct dosing recommendations concerning the utilization of either check here propoxyphene by yourself or together with acetaminophen in sufferers with hepatic or renal impairment as a purpose read more of degree of impairment. Greater plasma concentrations and/or delayed elimination might manifest in case of impaired hepatic perform and/or impaired renal purpose (see CLINICAL PHARMACOLOGY).

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In addition, narcotics generate adverse reactions which may obscure the scientific study course of sufferers with head injuries.

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Zidovudine: The pharmacologic outcomes of zidovudine might be diminished because of Increased nonhepatic or renal clearance of zidovudine.

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